Registrar is open source software for accurate spatial registration of multiple overlapping stacks of images, registration of stacks of images acquired in a time-lapse manner, and registration of image plains within individual stacks. Registrar provides a utility for registration based on translation, rigid, affine, and B-spline transformations. This software was developed by Seyed M.M. Kahaki with input from other members of the Neurogeometry group.

Installation and System Requirements

Registrar can be downloaded at https://github.com/neurogeometry/registrar. Start MATLAB, navigate to the software folder, and run Registrar in the MATLAB command window. Registrar is designed to run sequentially or in parallel, on a PC or a cluster.

Sample Data

To test the software, download RegistrarSampleData.zip (~160 MB) and extract its components. This folder includes the Neocortical Layer 1 Axons dataset of the DIADEM Competition, which can be used along with spatial registration.

Demo